Myeloid Neoplasms with Elevated Plasmacytoid Dendritic Cell Differentiation Reflect the Maturation Process of Dendritic Cells
نویسندگان
چکیده
منابع مشابه
Comparison of Several Maturation Inducing Factors in Dendritic Cell Differentiation
Background: Dendritic cells (DCs) are professional antigen presenting cells that have an important role in the initiation of immune response. The use of maturation factors in dendritic cell differentiation provides a promising approach in immunotherapy. Objective: In this study, we compared tumor necrosis factor-α, polyribocytidylic acid, lipopolysacharide and CpG oligonucleotides in inducing d...
متن کاملBlastic plasmacytoid dendritic cell neoplasms
1Department of Hematology, Medical University of Łódź Head of Department: prof. Tadeusz Robak, MD, PhD 2Department of Experimental Hematology, Medical University of Łódź Head of Department: prof. Piotr Smolewski, MD, PhD 3Department of Pathology, Medical University of Łódź Head of Department: prof. Radzisław Kordek, MD, PhD 4Department of Cytogenetic, The Maria Skłodowska-Curie Memorial Cancer ...
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Background: Angiolymphoid hyperplasia with eosinophilia (ALHE) is characterized by irregularly-shaped blood vessels with an inflammatory infiltrate. While absent from normal skin, plasmacytoid dendritic cells (pDCs) infiltrate the skin upon injury and during several infectious, inflammatory, and neoplastic entities. In addition to providing anti-viral resistance, pDCs link the innate and adapti...
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Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematodermic myeloid malignancy that is known to be derived from plasmacytoid dendritic cells which are characterized by expression of CD4, CD56, and more specific markers such as CD123. Here, the authors present three cases of BPDCN diagnosed in the past two years and address different available diagnostic modalities such as morpho...
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Background: Falciparum malaria is a severe health burden worldwide. Antigen presenting cells are reported to be affected by erythrocytic stage of the parasite. Malarial hemozoin (HZ), a metabolite of malaria parasite, has adjuvant properties and may play a role in the induction of immune response against the parasite. Objective: To determine the immunological impact of hemozoin on the capacity ...
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ژورنال
عنوان ژورنال: Cytometry Part A
سال: 2019
ISSN: 1552-4922,1552-4930
DOI: 10.1002/cyto.a.23953